Endocrine Abstracts

Cancer cells show different metabolic requirements than normal cells, being the high rate of glucose uptake one of the most important aspects. An increase in glucose uptake has been associated mainly with GLUT1 overexpression but may also involve other transporters including GLUT4, whose presence in prostate cancer cells was recently discovered in our laboratory. Moreover, androgens stimulate anabolic synthesis and increase glucose uptake. Despite this, the regulation of GLUT ...